How to call a script without system()

Is it possible? I know system calls are horrendously vulnerable to viruses and malicious users...So I'm wondering, can I call my python script without system?
You can use the Python API
closed account (1yR4jE8b)
What I've been doing lately is actually building GUI front ends for my applications using PyQT which is ridiculously simple and then for any serious computation I would call C/C++ routines from Python. It works surprisingly well, actually.
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